Treatment of Patients with Severe Sepsis and Septic Shock: Current Evidence-Based Practices

Jisoo Lee; Mitchell M Levy

Treatment of Patients with Severe Sepsis and Septic Shock: Current Evidence-Based Practices

R I Med J (2013). 2019 Dec 2;102(10):18-21.

Authors

Jisoo Lee¹, Mitchell M Levy¹

Affiliation

¹ Division of Pulmonary, Critical Care and Sleep Medicine, Warren Alpert Medical School of Brown University, Providence, RI.

PMID: 31795528

Abstract

Sepsis remains a field of active research with many unknown and unanswered questions. Over the past few decades, advancements in sepsis management have led to improved mortality and morbidity. This article will review the current evidence-based practices of the treatment of sepsis and septic shock. It will also critically appraise some of the current controversies in sepsis management, such as fluids, steroids, early vasopressors, early goal-directed therapy and immunotherapy.

Keywords: controversies; management; sepsis; septic shock.

Publication types

Review

MeSH terms

Disease Management
Drug Therapy, Combination
Early Goal-Directed Therapy / methods
Evidence-Based Practice / trends*
Fluid Therapy / methods
Humans
Immunotherapy / methods
Sepsis / therapy*
Shock, Septic / therapy*
Steroids / therapeutic use
Vasoconstrictor Agents / therapeutic use

Substances

Steroids
Vasoconstrictor Agents