[Sodium metabolism: An update in 2019]

Nephrol Ther. 2020 Mar;16(2):77-82. doi: 10.1016/j.nephro.2019.06.004. Epub 2019 Nov 29.
[Article in French]

Abstract

The classical theory of sodium metabolism considers mostly its role on the extracellular volume according to a daily response to the variations of salt intake, correlated to the variations of water volume. Recent works consider sodium tissular storage. This non-osmotic pool could play a role in blood pressure regulation and in immunity mechanisms. The regulation modalities could be more complex, organised over the long term, with a modification of the sodium-water relationship. The aim of this article is to give a new insight on sodium metabolism, based on recent works, especially on the role and regulation of non osmotic tissular sodium.

Keywords: Aldosterone; Aldostérone; Blood pressure; Non-osmotic sodium; Pression artérielle; Sodium; Sodium non osmotique.

Publication types

  • Review

MeSH terms

  • Humans
  • Sodium / metabolism*

Substances

  • Sodium