Severe chronic rhinosinusitis in children should alert clinicians and extensive CFTR genotyping should be performed. We propose that thorough clinical and functional assessment in severe chronic rhinosinusitis is valuable to discover rare mutations which could be treated by CFTR correctors to postpone pulmonary infection.
Keywords: CFTR; chronic rhinosinusitis; cystic fibrosis; functional studies.
© 2019 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.