The place of secondary complete cytoreductive surgery in advanced ovarian cancer

Horm Mol Biol Clin Investig. 2019 Nov 29;41(3). doi: 10.1515/hmbci-2019-0030.

Abstract

Despite optimal treatment, three-quarters of the patients with advanced ovarian cancer, experiment relapse and its treatment has become a public health issue. Initially debated, surgery is gaining legitimacy in the treatment of late relapse patients, compared to chemotherapy alone. Secondary complete cytoreduction should be proposed only to a highly selected population. The type of surgery depends on the recurrence localization and the relapse extension in the pelvis and to other organs. Innovating techniques of surgery have become widespread including heated intra peritoneal chemotherapy (HIPEC), laparoscopy and robotic surgery. These specialized treatments should only be carried out in reference centers by oncological surgeons.

Keywords: ovarian cancer; recurrence; secondary cytoreductive surgery.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / therapeutic use
  • Combined Modality Therapy
  • Cytoreduction Surgical Procedures / methods*
  • Female
  • Humans
  • Hyperthermia, Induced / methods
  • Laparoscopy / methods
  • Ovarian Neoplasms / pathology
  • Ovarian Neoplasms / surgery*
  • Ovarian Neoplasms / therapy
  • Robotic Surgical Procedures / methods

Substances

  • Antineoplastic Agents