An Insightful 10-year Recollection Since the Emergence of the 5-steps Rule

Kuo-Chen Chou

doi:10.2174/1381612825666191129164042

An Insightful 10-year Recollection Since the Emergence of the 5-steps Rule

Curr Pharm Des. 2019;25(40):4223-4234. doi: 10.2174/1381612825666191129164042.

Author

Kuo-Chen Chou^{1

2}

Affiliations

¹ Gordon Life Science Institute, Boston, Massachusetts 02478, United States.
² Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu, China.

PMID: 31782354
DOI: 10.2174/1381612825666191129164042

Abstract

Objective: One of the most challenging and also the most difficult problems is how to formulate a biological sequence with a vector but considerably keep its sequence order information.

Methods: To address such a problem, the approach of Pseudo Amino Acid Components or PseAAC has been developed.

Results and conclusion: It has become increasingly clear via the 10-year recollection that the aforementioned proposal has been indeed very powerful.

Keywords: 5-steps rule; PseAAC; PseKNC; biological sequence; byproducts; distorted key theory..

Publication types

Review
Retracted Publication

MeSH terms

Algorithms*
Amino Acids
Computational Biology*
Protein Conformation
Sequence Analysis, Protein / methods*

Substances

Amino Acids