Computational insight into the conformational transition of human toll-like receptor 8 in the agonist-induced activation processes

J Biomol Struct Dyn. 2020 Nov;38(18):5537-5543. doi: 10.1080/07391102.2019.1699448. Epub 2019 Dec 12.

Authors

Shuheng Huang^{1

2}, Hu Mei^{1

2}, Linxin Chen², Tingting Shi², Zuyin Kuang², Yu Heng², Yonghong Zhang³, Laichun Lu^{1

2}

Affiliations

¹ Key Laboratory of Biorheological Science and Technology (Ministry of Education), Chongqing University, Chongqing, China.
² College of Bioengineering, Chongqing University, Chongqing, China.
³ Medicine Engineering Research Center, College of Pharmacy, Chongqing Medical University, Chongqing, China.

PMID: 31779534
DOI: 10.1080/07391102.2019.1699448

Abstract

Communicated by Ramaswamy H. Sarma.

Publication types

Letter

MeSH terms

Humans
Molecular Conformation*
Molecular Dynamics Simulation*
Toll-Like Receptor 8*

Substances

Toll-Like Receptor 8