Defining the biological responses of IL-6 by the study of a novel IL-6 receptor chain immunodeficiency

Affiliations

• ¹ Pediatrics Department A, Soroka University Medical Center, Be'er Sheva, Israel; Immunology Clinic, Soroka University Medical Center, Be'er Sheva, Israel; Primary Immunodeficiency Research Laboratory, Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel. Electronic address: amitna@clalit.org.il.
• ² Canadian Centre for Primary Immunodeficiency and the Jeffrey Modell Research Laboratory for the Diagnosis of Primary Immunodeficiency, the Hospital for Sick Children, Toronto, Ontario, Canada; Division of Immunology and Allergy, Department of Paediatrics, the Hospital for Sick Children and the University of Toronto, Toronto, Ontario, Canada.
• ³ Immunology Clinic, Soroka University Medical Center, Be'er Sheva, Israel.
• ⁴ Pediatrics Department A, Soroka University Medical Center, Be'er Sheva, Israel; Canadian Centre for Primary Immunodeficiency and the Jeffrey Modell Research Laboratory for the Diagnosis of Primary Immunodeficiency, the Hospital for Sick Children, Toronto, Ontario, Canada; Division of Immunology and Allergy, Department of Paediatrics, the Hospital for Sick Children and the University of Toronto, Toronto, Ontario, Canada.
• ⁵ Primary Immunodeficiency Research Laboratory, Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
• ⁶ Department of Pediatrics, E. Wolfson Medical Center, Holon, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
• ⁷ Department of Clinical Biochemistry, Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
• ⁸ Morris Kahn Laboratory of Human Genetics, National Institute for Biotechnology in the Negev and Faculty of Health Sciences, Ben-Gurion University of the Negev, Be'er Sheva, Israel.
• ⁹ Canadian Centre for Primary Immunodeficiency and the Jeffrey Modell Research Laboratory for the Diagnosis of Primary Immunodeficiency, the Hospital for Sick Children, Toronto, Ontario, Canada; Division of Immunology and Allergy, Department of Paediatrics, the Hospital for Sick Children and the University of Toronto, Toronto, Ontario, Canada. Electronic address: chaim.roifman@sickkids.ca.