Kinky integrins reveal a new wrinkle in neutrophil activation

Vasilios A Morikis; Kathryn Rivara; Scott I Simon

doi:10.1002/JLB.3CE1019-273R

Kinky integrins reveal a new wrinkle in neutrophil activation

J Leukoc Biol. 2020 Feb;107(2):167-169. doi: 10.1002/JLB.3CE1019-273R. Epub 2019 Nov 28.

Authors

Vasilios A Morikis¹, Kathryn Rivara¹, Scott I Simon¹

Affiliation

¹ UC Davis, Davis, California, USA.

PMID: 31777979
DOI: 10.1002/JLB.3CE1019-273R

Abstract

Discussion on the flexible kink produced in the β₂ -integrin transmembrane domain blocking mechanotransduction of signals necessary for neutrophil arrest and spreading.

Publication types

Editorial
Comment

MeSH terms

CD18 Antigens*
Cell Adhesion
Integrins
Mechanotransduction, Cellular
Neutrophil Activation*
Neutrophils

Substances

CD18 Antigens
Integrins