A novel use of pneumococcal urinary antigen detection kits to identify Streptococcus pneumoniae cultures misidentified by the VITEK-2 system

Trop Doct. 2020 Apr;50(2):146-149. doi: 10.1177/0049475519889717. Epub 2019 Nov 26.

Abstract

Streptococcus pneumoniae infections continue to be an important cause of morbidity and mortality in low-and middle-income countries. Differentiating S. pneumoniae from viridans group streptococci is essential to ensure appropriate antibiotic therapy. Conventional microbial identification tests can often misidentify the two groups. We used a common pneumococcal urinary antigen test to identify S. pneumoniae that were misidentified by the VITEK 2. The performance of the test was similar to the pneumococcal latex agglutination test.

Keywords: Streptococcus pneumoniae; Streptococcus pneumoniae culture; VITEK 2 misidentification; pneumococcal antigen test; pneumococcal urinary antigen detection.

MeSH terms

  • Anti-Bacterial Agents / therapeutic use
  • Antigens, Bacterial / blood
  • Antigens, Bacterial / urine*
  • Bacteriological Techniques
  • Humans
  • Latex Fixation Tests
  • Pneumococcal Infections / diagnosis*
  • Pneumococcal Infections / drug therapy
  • Pneumococcal Infections / urine
  • Reagent Kits, Diagnostic*
  • Species Specificity
  • Streptococcus pneumoniae / immunology
  • Streptococcus pneumoniae / isolation & purification*

Substances

  • Anti-Bacterial Agents
  • Antigens, Bacterial
  • Reagent Kits, Diagnostic