Targeted therapy in oncology patients and skin: Pharmaceutical and dermocosmetic management

J Cosmet Dermatol. 2020 Apr;19(4):782-788. doi: 10.1111/jocd.13211. Epub 2019 Nov 26.

Abstract

Background: Numerous oncology patients who receive targeted therapy suffer from the skin adverse effects induced. Novel agents, that is tyrosine kinase inhibitors and RAS-RAF-MEK-ERK pathway, have given good results in patient survival while decreasing the systemic toxicities in comparison to conventional cytotoxic chemotherapy, but are also related to skin adverse effects.

Aims: In this article, we highlighted the importance of specific pharmaceutical and dermocosmetic management of the untoward events of targeted therapy.

Conclusion: The combination of Oncodermatology, Psychodermatology, Cosmetic Dermatology, Cosmetic Science, Dermatopharmacology and Aesthetic Science can offer a lot for the prevention or early relief of the cutaneous adverse effects in oncology patients receiving targeted therapy.

Keywords: cosmetics; dermocosmetic management; oncology; pharmaceuticals; skin adverse effects.

Publication types

  • Review

MeSH terms

  • Antineoplastic Agents / adverse effects*
  • Cosmetics / therapeutic use*
  • Dermatologic Agents / therapeutic use*
  • Drug Eruptions / drug therapy*
  • Drug Eruptions / etiology
  • Humans
  • Molecular Targeted Therapy / adverse effects
  • Neoplasms / drug therapy*
  • Skin / drug effects

Substances

  • Antineoplastic Agents
  • Cosmetics
  • Dermatologic Agents