Intraperitoneal Rupture of a Synovial Sarcoma of the Kidney

Andrew Stamm; Neal Conti; Semra Olgac; John Paul Flores; Michael J Wagner; Paul Kozlowski

Intraperitoneal Rupture of a Synovial Sarcoma of the Kidney

Rev Urol. 2019;21(2-3):136-140.

Authors

Andrew Stamm¹, Neal Conti¹, Semra Olgac¹, John Paul Flores¹, Michael J Wagner², Paul Kozlowski¹

Affiliations

¹ Virginia Mason Medical Center Seattle, WA.
² University of Washington Medical Center Seattle, WA.

PMID: 31768144
PMCID: PMC6864906

Abstract

Primary renal synovial sarcoma is an aggressive, extremely rare disease. Nearly all reported cases are characterized by SYT-SSX gene translocation (X;18)(p11;q11). We describe the case of a 43-year-old woman who presented with an intraperitoneal rupture of this rare sarcoma followed by a right radical nephrectomy. Follow-up imaging 1 month after surgery revealed peritoneal carcinomatosis. She began systemic chemotherapy with doxorubicin and dacarbazine, progressed after 3 months, and is currently receiving single-agent ifosfamide. Only one instance of intraperitoneal rupture has been reported previously. This case report contributes to the characterization of this rare disease.

Keywords: Kidney cancer; Oncology; Renal synovial sarcoma.