1 Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine and Health, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK. graeme.black@manchester.ac.uk.
2 NW Genomic Laboratory Hub, St Mary's Hospital, Manchester Centre for Genomic Medicine, Manchester Academic Health Sciences Centre, Manchester University NHS Foundation Trust, Manchester, UK. graeme.black@manchester.ac.uk.
3 Manchester Centre for Genomic Medicine, Central Manchester University Hospitals NHS Foundation Trust, Manchester Academic Health Science Centre, St. Mary's Hospital, Manchester, UK. graeme.black@manchester.ac.uk.
4 Academy of Medical Royal Colleges, 10 Dallington St, London, UK.
5 Ophthalmology Department, University of Dundee, Ninewells Hospital, Dundee, UK.
6 Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, University Hospital Southampton, Tremona Road, Southampton, England, UK.
7 Southampton Eye Unit, University Hospital Southampton NHS Foundation Trust, University Hospital Southampton, Southampton, England, UK.