Intracardiac metastasis from unknown uterine cervical cancer with severe thrombocytopenia

J Card Surg. 2020 Feb;35(2):473-476. doi: 10.1111/jocs.14362. Epub 2019 Nov 25.

Abstract

Introduction: Cardiac metastasis is relatively common in malignant neoplasms, such as lung cancers, breast cancers, melanomas, lymphomas, and leukemias. In contrast, cardiac metastasis of uterine cervical cancer, solitary metastasis to the heart, and tumors inducing severe thrombocytopenia are rare.

Case report: The present patient was a 52-year-old female who was diagnosed with a solitary cardiac tumor prior to uterine cervical cancer and presented with severe thrombocytopenia. Our case had two remarkable aspects: 1) successful treatment under the condition of severe thrombocytopenia in association with the presence of a cardiac tumor, and survival without recurrence of the carcinoma one year after surgery; and 2) a solitary cardiac metastatic tumor larger than the primary uterine cervix carcinoma.

Comment: we report an extremely rare case of solitary cardiac metastasis of uterine cervical cancer, which wassuccessfully treated. One year after cardiac surgery, the patient is alive without recurrence of the carcinoma.

Keywords: cardiac tumor; intracardiac metastasis; thrombocytopenia; uterine cervical cancer.

Publication types

  • Case Reports

MeSH terms

  • Carcinoma, Squamous Cell / diagnostic imaging
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / secondary*
  • Carcinoma, Squamous Cell / therapy
  • Cardiac Surgical Procedures / methods
  • Cisplatin / administration & dosage
  • Combined Modality Therapy
  • Female
  • Heart Neoplasms / diagnostic imaging
  • Heart Neoplasms / pathology
  • Heart Neoplasms / secondary*
  • Heart Neoplasms / therapy*
  • Humans
  • Platelet Transfusion
  • Rare Diseases
  • Severity of Illness Index
  • Thrombocytopenia / etiology*
  • Thrombocytopenia / therapy
  • Treatment Outcome
  • Uterine Neoplasms / complications
  • Uterine Neoplasms / diagnostic imaging
  • Uterine Neoplasms / pathology*
  • Uterine Neoplasms / therapy*

Substances

  • Cisplatin