[A women with aplastic anemia developed chronic inflammatory demyelinating polyneuropathy]

Rinsho Shinkeigaku. 2019 Dec 25;59(12):818-822. doi: 10.5692/clinicalneurol.cn-001312. Epub 2019 Nov 23.
[Article in Japanese]

Abstract

A 66-year-old female developed chronic inflammatory demyelinating polyneuropathy (CIDP) one year after the diagnosis of aplastic anemia. High-dose intravenous immunoglobulin (IVIg) therapy, followed by IVIg maintenance therapy, rapidly improved her weakness and hyperesthesia in four extremities. In addition, pancytopenia caused by aplastic anemia also improved following IVIg treatment in parallel. This is the first report to show the co-existence of CIDP and aplastic anemia, and a common pathomechanism may be present in these two rare autoimmune disorders.

Keywords: aplastic anemia; chronic inflammatory demyelinating polyneuropathy; immunoglobulin.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anemia, Aplastic / complications
  • Anemia, Aplastic / drug therapy*
  • Anemia, Aplastic / etiology*
  • Autoimmunity
  • Female
  • Humans
  • Immunoglobulins, Intravenous / administration & dosage*
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / drug therapy*
  • Polyradiculoneuropathy, Chronic Inflammatory Demyelinating / etiology*
  • Treatment Outcome

Substances

  • Immunoglobulins, Intravenous