Multiple mycotic aneurysms of the aortic root after aortic valve replacement

Monica De Gaspari; Cristina Basso; Martina Perazzolo Marra; Gaetano Thiene; Stefania Rizzo

doi:10.1016/j.carpath.2019.107152

Multiple mycotic aneurysms of the aortic root after aortic valve replacement

Cardiovasc Pathol. 2020 Jan-Feb:44:107152. doi: 10.1016/j.carpath.2019.107152. Epub 2019 Oct 24.

Authors

Monica De Gaspari¹, Cristina Basso², Martina Perazzolo Marra¹, Gaetano Thiene¹, Stefania Rizzo¹

Affiliations

¹ Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padova, Italy.
² Department of Cardiac, Thoracic, Vascular Sciences and Public Health, University of Padua, Padova, Italy. Electronic address: cristina.basso@unipd.it.

PMID: 31760245
DOI: 10.1016/j.carpath.2019.107152

Abstract

A 74-year-old woman with severe aortic valve stenosis underwent aortic valve replacement with a pericardial bioprosthesis. Histological analysis of the excised valve showed dystrophic calcification associated with signs of healed infective endocarditis. Two months later, the patient died due to congestive heart failure. Autopsy revealed a bowel infarction and the presence of multiple mycotic aneurysms of the aortic root with mural thrombosis, which were unnoticed during the patient hospital stay and surgical window.

Keywords: Aortic valve replacement; Endocarditis; Mycotic aneurysm; Postmortem diagnosis.

Publication types

Case Reports

MeSH terms

Aged
Aneurysm, Infected / microbiology*
Aneurysm, Infected / pathology
Aneurysm, Infected / therapy
Aortic Aneurysm / microbiology*
Aortic Aneurysm / pathology
Aortic Aneurysm / therapy
Aortic Valve Stenosis / surgery*
Autopsy
Bioprosthesis / adverse effects*
Cause of Death
Fatal Outcome
Female
Heart Valve Prosthesis / adverse effects*
Heart Valve Prosthesis Implantation / adverse effects*
Heart Valve Prosthesis Implantation / instrumentation
Humans
Klebsiella Infections / microbiology*
Klebsiella Infections / pathology
Klebsiella Infections / therapy
Klebsiella pneumoniae / isolation & purification*
Prosthesis-Related Infections / microbiology*
Prosthesis-Related Infections / pathology
Prosthesis-Related Infections / therapy