Imaging of Posttraumatic Stress Disorder

Kouhei Kamiya; Osamu Abe

doi:10.1016/j.nic.2019.09.010

Imaging of Posttraumatic Stress Disorder

Neuroimaging Clin N Am. 2020 Feb;30(1):115-123. doi: 10.1016/j.nic.2019.09.010. Epub 2019 Nov 9.

Authors

Kouhei Kamiya¹, Osamu Abe²

Affiliations

¹ Department of Radiology, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan. Electronic address: kkamiya-tky@umin.ac.jp.
² Department of Radiology, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.

PMID: 31759567
DOI: 10.1016/j.nic.2019.09.010

Abstract

This review summarizes current knowledge obtained from psychoradiological studies of posttraumatic stress disorder (PTSD). We first focus on 3 key anatomic structures (hippocampus, amygdala, and medial prefrontal cortex) and the functional circuits to which they contribute. In addition, we discuss the triple-network model, a widely accepted neurobiological model of PTSD that explains the vast majority of neuroimaging findings, as well as their interactions and relationships to functional disruptions in PTSD.

Keywords: Diffusion MR imaging; Functional MR imaging; Posttraumatic stress disorder; Psychoradiology; Structural MR imaging.

Publication types

Review

MeSH terms

Amygdala / diagnostic imaging
Amygdala / pathology*
Emotional Regulation
Executive Function
Hippocampus / diagnostic imaging
Hippocampus / pathology*
Humans
Magnetic Resonance Imaging
Neuroimaging / methods*
Prefrontal Cortex / diagnostic imaging
Prefrontal Cortex / pathology*
Risk Factors
Stress Disorders, Post-Traumatic / diagnostic imaging
Stress Disorders, Post-Traumatic / pathology*