Low socioeconomic status and formula feeding directly correlate with increased incidence of hypertrophic pyloric stenosis

J Pediatr Surg. 2019 Dec;54(12):2498-2502. doi: 10.1016/j.jpedsurg.2019.08.044. Epub 2019 Nov 6.

Abstract

Purpose: The purpose of this analysis was to determine if a correlation exists between socioeconomic status (SES) and pyloric stenosis (PS) as well as between PS and feeding method.

Methods: Data was collected retrospectively from the electronic medical record. Patients were included if they resided in a county in Illinois where our institution maintains >10% visit share, were < 1 year in age, and received a pyloromyotomy from January 2011 to May 2018. Patient addresses were geocoded and merged with county and tract-level census data. A control group was matched on gender, race, tract level, median household income (MHI), and age. Feeding method for each group was collected. Univariate analysis and multivariate analyses were employed.

Results: SES was explored using MHI. After controlling for gender, age, race, and institution adjusted tract size, the association between MHI and pyloromyotomy remained significant. As MHI decreased, the odds of having a PS case increased. Additionally, the PS incidence rate increased as MHI decreased. Patients who were exclusively formula fed were more likely to have PS.

Conclusion: Pyloric stenosis had a direct correlation with SES as defined by MHI. As MHI decreased, the rates of PS increased. In addition, breastfeeding was protective, independent of MHI.

Type of study: Prognosis study.

Level of evidence: Level II.

Keywords: Breastfeeding; Pyloric stenosis; Socioeconomic status.

MeSH terms

  • Breast Feeding / statistics & numerical data*
  • Female
  • Humans
  • Illinois / epidemiology
  • Incidence
  • Income*
  • Infant
  • Infant Formula / statistics & numerical data*
  • Infant, Newborn
  • Male
  • Neoplasm Staging
  • Pyloric Stenosis, Hypertrophic / epidemiology*
  • Pyloric Stenosis, Hypertrophic / surgery
  • Pyloromyotomy
  • Retrospective Studies