How mitochondrial DNA-driven changes to chromosomal DNA methylation add a layer of complexity to mitochondrial disease

Epigenomics. 2019 Dec;11(16):1749-1751. doi: 10.2217/epi-2019-0310. Epub 2019 Nov 22.

Author

Boel De Paepe¹

Affiliation

¹ Neuromuscular Reference Center, Ghent University Hospital, Corneel Heymanslaan 10, Ghent 9000, Belgium.

PMID: 31755745
DOI: 10.2217/epi-2019-0310

No abstract available

Keywords: mitochondrial DNA haplogroups; mitochondrial DNA heteroplasmy; mitochondrial DNA-driven epigenetic regulation; mitochondrial disease.

Publication types

Editorial

MeSH terms

Chromosomes
DNA Methylation
DNA, Mitochondrial*
Humans
Mitochondrial Diseases / genetics*

Substances

DNA, Mitochondrial