2-Styrylquinoline-based two-photon AIEgens for dual monitoring of pH and viscosity in living cells

J Mater Chem B. 2019 Dec 11;7(48):7771-7775. doi: 10.1039/c9tb02036e.

Abstract

A new class of aggregation-induced emission (AIE) fluorophores HAPHs with excellent two-photon properties is developed from styrylquinoline. Among them, the probe HAPH-1 exhibits good sensitivity towards pH and viscosity and has been successfully used for simultaneous pH and viscosity detection in living cells through two-photon microscopy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cells / metabolism
  • Cells, Cultured
  • Diagnostic Imaging / methods
  • Fluorescent Dyes / chemistry*
  • Humans
  • Hydrogen-Ion Concentration*
  • Photons
  • Quinolines / chemistry*
  • Viscosity*

Substances

  • Fluorescent Dyes
  • Quinolines
  • styrylquinoline