Azole-resistant Aspergillus fumigatus in the hospital: Surveillance from flower beds to corridors

Chloé Godeau; Gabriel Reboux; Emeline Scherer; Audrey Laboissiere; Clothilde Lechenault-Bergerot; Laurence Millon; Steffi Rocchi

doi:10.1016/j.ajic.2019.10.003

Azole-resistant Aspergillus fumigatus in the hospital: Surveillance from flower beds to corridors

Am J Infect Control. 2020 Jun;48(6):702-704. doi: 10.1016/j.ajic.2019.10.003. Epub 2019 Nov 19.

Authors

Chloé Godeau¹, Gabriel Reboux², Emeline Scherer², Audrey Laboissiere¹, Clothilde Lechenault-Bergerot¹, Laurence Millon², Steffi Rocchi³

Affiliations

¹ Chrono-Environnement UMR CNRS 6249, Bourgogne Franche-Comté University, Besançon, France.
² Chrono-Environnement UMR CNRS 6249, Bourgogne Franche-Comté University, Besançon, France; Parasitology-Mycology Department, University Hospital, Besançon, France.
³ Chrono-Environnement UMR CNRS 6249, Bourgogne Franche-Comté University, Besançon, France; Parasitology-Mycology Department, University Hospital, Besançon, France. Electronic address: steffi.rocchi@univ-fcomte.fr.

PMID: 31753549
DOI: 10.1016/j.ajic.2019.10.003

Abstract

Screening has been performed for azole-resistant Aspergillus fumigatus in the indoor air of the hospital since 2015 and in soil and dust samples since January 2019. In total, 83 azole-resistant A fumigatus isolates with a TR₃₄/L98H mutation have been obtained: 1 from the air of the intensive care unit, 16 from the main corridors, 59 from pots of tulips imported from the Netherlands, and 5 from the soil of trees grown in pots.

Keywords: TR34/L98H; Triazole resistance; Tulips.

MeSH terms

Antifungal Agents / pharmacology
Aspergillus fumigatus* / genetics
Azoles* / pharmacology
Drug Resistance, Fungal
Flowers
Fungal Proteins / genetics
Genotype
Hospitals
Humans
Microbial Sensitivity Tests
Netherlands

Substances

Antifungal Agents
Azoles
Fungal Proteins