Biomarkers Associated with Aortic Stenosis and Structural Bioprosthesis Dysfunction

Abstract

Prediction of patients at risk of aortic valve stenosis (AS), AS progression rate, and aortic bioprosthesis dysfunction are of major importance for clinical management and/or prevention. Many imaging modalities may be used; however, they may not be conclusive or available for all patients. Circulating biomarkers are easily available and may be related to a disease or process such as aortic valve calcification or associated with a risk factor of the disease. This article reviews current blood biomarkers associated with aortic valve stenosis/calcification and bioprosthesis dysfunction.

Keywords: Aortic stenosis; Biomarkers; Calcium; Hemostasis; Lipid; Platelets.