Role of Surgery for Metastatic Melanoma

Abstract

Complete surgical resection of metastatic melanoma has a known survival benefit. Treatment of metastatic melanoma, however, has become increasingly complex with the introduction of targeted treatments and immune checkpoint inhibitors. Integration of systemic medical therapy and surgical resection has shown promising results, with significantly improved long-term survivals. Results from current clinical trials are awaited to help further delineate the sequence and combination of systemic therapy and surgery.

Keywords: Metastasectomy; Metastatic melanoma; Oligometastatic melanoma; Stage IV melanoma.