Label-Free Proteome Profiling as a Quantitative Target Identification Technique for Bioactive Small Molecules

Biochemistry. 2020 Jan 28;59(3):213-215. doi: 10.1021/acs.biochem.9b00975. Epub 2019 Nov 20.

Authors

Kyung Tae Hong^{1

2}, Jun-Seok Lee^{1

2}

Affiliations

¹ Molecular Recognition Research Center , Korea Institute of Science and Technology (KIST) , Hwarangro 14 gil 5 , Seunbguk-gu, Seoul 02792 , Republic of Korea.
² Bio-Med Program , KIST-School UST , Hwarangro 14 gil 5 , Seungbuk-gu, Seoul 02792 , Republic of Korea.

PMID: 31746590
DOI: 10.1021/acs.biochem.9b00975

No abstract available

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

DNA Repair Enzymes / genetics
Gene Expression Profiling*
Humans
Hypertension / drug therapy
Mass Spectrometry
Phosphoric Monoester Hydrolases / genetics
Proteome / drug effects
Proteome / genetics*
Proteomics*
Reserpine / analogs & derivatives
Reserpine / chemistry
Reserpine / therapeutic use
Small Molecule Libraries / therapeutic use

Substances

Proteome
Small Molecule Libraries
Reserpine
Phosphoric Monoester Hydrolases
8-oxodGTPase
DNA Repair Enzymes
syrosingopine