Female Sex Is Protective in a Preclinical Model of Heart Failure With Preserved Ejection Fraction

Circulation. 2019 Nov 19;140(21):1769-1771. doi: 10.1161/CIRCULATIONAHA.119.042267. Epub 2019 Nov 18.
No abstract available

Keywords: heart failure; sex.

Publication types

  • Letter
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood Pressure
  • Diet, High-Fat
  • Disease Models, Animal
  • Enzyme Inhibitors
  • Female
  • Glucose Intolerance / etiology
  • Glucose Intolerance / physiopathology
  • Heart Failure / enzymology
  • Heart Failure / etiology
  • Heart Failure / physiopathology*
  • Humans
  • Hypertension / etiology
  • Hypertension / physiopathology
  • Male
  • Mice, Inbred C57BL
  • NG-Nitroarginine Methyl Ester
  • Nitric Oxide Synthase / antagonists & inhibitors
  • Nitric Oxide Synthase / metabolism
  • Obesity / etiology
  • Obesity / physiopathology
  • Risk Factors
  • Sex Characteristics
  • Sex Factors
  • Stroke Volume*
  • Ventricular Function, Left*
  • Ventricular Remodeling*
  • Weight Gain

Substances

  • Enzyme Inhibitors
  • Nitric Oxide Synthase
  • NG-Nitroarginine Methyl Ester