1 Division of Anesthesiology, Department of Anesthesiology, Pharmacology, Intensive Care, and Emergency Medicine, Geneva University Hospitals, Geneva, Switzerland Intensive Care Department, Hospital Universitari de Bellvitge, L'Hospitalet de Llobregat, Barcelona, Spain, and Institut d'Investigació Biomèdica Bellvitge (IDIBELL), L'Hospitalet de Llobregat, Barcelona, Spain Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy, and Vita-Salute San Raffaele University, Milan, Italy.