[Nutrition in children with continuous renal replacement therapy]

An Pediatr (Engl Ed). 2020 Apr;92(4):208-214. doi: 10.1016/j.anpedi.2019.08.006. Epub 2019 Nov 13.
[Article in Spanish]

Abstract

Introduction: The aim of this study was to analyse the nutritional state, diet and gastrointestinal complications of children that require continuous renal replacement therapy (CRRT).

Material and methods: A retrospective analysis of a database, which included the information about patients who required CRRT between the years 2013 and 2017. Data were collected on the replacement technique, type of nutrition, calorie and protein intake, gastrointestinal complications, and clinical course.

Results: A total of 65 children (61.5% male) were treated with CRRT, and 24 patients (37%) also needed ECMO support. Just over one-quarter (27.7%) of patients had a weight less than P3, and 48.4% of them a height less than P3. At the beginning of the technique, 31 children (47.7%) received enteral nutrition, at the end, there were 52 patients receiving enteral nutrition (80%). The transpyloric tube was used to provide nutrition in 76% of the cases. The median caloric intake was 63kcal/kg/day, and the protein intake was 1.6g/kg/day. There were gastrointestinal difficulties during the process in 48 patients (73.8%), with 29 (44.6%) patients being diagnosed with gastric distension or excessive gastric remains, 22 (33.8%) with constipation, 8 (12.3%) with vomiting, and 4 (6.1%) diarrhoea. One patient treated with ECMO presented with intestinal ischaemia. Enteral nutrition was cancelled in 3 patients (4.6%) due to the complications. There was no relationship between complications and type of diet or ECMO assistance.

Conclusions: A high percentage of children treated with CRRT showed undernutrition but they had adequate tolerance to the enteral nutrition. Although the gastrointestinal complications percentage was high in few subjects, these complications are the reason why enteral nutrition was stopped.

Keywords: Children; Complicaciones digestivas; Continuous renal replacement therapy; Extracorporeal membrane oxygenation; Gastrointestinal complications; Niños; Nutrición; Nutrition; Oxigenación por membrana extracorpórea; Técnicas de depuración extrarrenal continua.

MeSH terms

  • Acute Disease
  • Adolescent
  • Child
  • Child, Preschool
  • Chronic Disease
  • Continuous Renal Replacement Therapy / adverse effects*
  • Continuous Renal Replacement Therapy / methods
  • Databases, Factual
  • Diet*
  • Extracorporeal Membrane Oxygenation
  • Female
  • Gastrointestinal Diseases / diagnosis
  • Gastrointestinal Diseases / epidemiology
  • Gastrointestinal Diseases / etiology*
  • Humans
  • Infant
  • Male
  • Malnutrition / diagnosis
  • Malnutrition / epidemiology
  • Malnutrition / etiology*
  • Nutritional Status*
  • Renal Insufficiency / complications
  • Renal Insufficiency / therapy*
  • Retrospective Studies
  • Treatment Outcome