Generation of two induced pluripotent stem cell lines (NHLBIi001-A and NHLBIi001-B) from a healthy Caucasian female volunteer with normal cardiac function

Kira Patterson; Jeanette Beers; Kaari L Linask; Yongshun Lin; Shahin Hassanzadeh; Michael N Sack; Jizhong Zou

doi:10.1016/j.scr.2019.101627

Generation of two induced pluripotent stem cell lines (NHLBIi001-A and NHLBIi001-B) from a healthy Caucasian female volunteer with normal cardiac function

Stem Cell Res. 2019 Dec:41:101627. doi: 10.1016/j.scr.2019.101627. Epub 2019 Nov 1.

Authors

Kira Patterson¹, Jeanette Beers¹, Kaari L Linask¹, Yongshun Lin¹, Shahin Hassanzadeh², Michael N Sack², Jizhong Zou³

Affiliations

¹ iPSC Core, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
² Cardiovascular Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA.
³ iPSC Core, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA. Electronic address: zouj2@mail.nih.gov.

Abstract

Human-derived induced pluripotent stem cells (iPSCs) have proven to be indispensable in cardiovascular drug development, disease modeling, and developmental biology research. For this reason, it is particularly useful to develop wild-type iPSC lines to be used in experimental or control conditions. Here, we present two such cell lines generated from a sample of peripheral blood mononuclear cells (PBMCs) from a healthy patient with normal cardiac function.

Published by Elsevier B.V.

Publication types

Research Support, N.I.H., Intramural

MeSH terms

Cell Culture Techniques / methods*
Cell Line / cytology*
Female
Healthy Volunteers*
Heart / physiology*
Humans
Induced Pluripotent Stem Cells / cytology*
Middle Aged
White People*

Grants and funding

ZIC HL006145-07/ImNIH/Intramural NIH HHS/United States