Historical and new insights into pathogenesis of type 1 diabetes

Clin Exp Immunol. 2019 Dec;198(3):292-293. doi: 10.1111/cei.13396.

Abstract

In recent years, there have been exciting new insights into pathogenesis of type 1 diabetes in a number of areas of immunology. In this edition, a collection of four review articles are presented, which encompass new findings presented at the Immunology of Diabetes Society meeting in London 2018. The articles are focused particularly in 4 related areas of investigation, which include autoantibodies in type 1 diabetes, new autoantigenic targets for CD4 T cells, trafficking of immune cells to the pancreas and islet-immune interactions in the pancreas.

Publication types

  • Editorial
  • Introductory Journal Article

MeSH terms

  • Autoantibodies / immunology*
  • Autoantigens / immunology*
  • CD4-Positive T-Lymphocytes / immunology*
  • Diabetes Mellitus, Type 1 / immunology*
  • Diabetes Mellitus, Type 1 / pathology
  • Humans
  • Islets of Langerhans / immunology
  • Islets of Langerhans / pathology
  • Pancreas / immunology
  • Pancreas / pathology

Substances

  • Autoantibodies
  • Autoantigens