Annual banned-substance review - Analytical approaches in human sports drug testing

Drug Test Anal. 2020 Jan;12(1):7-26. doi: 10.1002/dta.2735. Epub 2020 Jan 15.

Abstract

Within the complex construct of today's antidoping work, continuously updated routine doping controls, as well as advancements in sampling and analysis have been of particular relevance and importance. New analytes of existing classes of prohibited substances are frequently included into sports drug testing assays, analytical approaches are optimized to allow for better sensitivities, selectivity, and/or faster turnaround times, and research dedicated to addressing analytical issues concerning scenarios of both (potentially) inadvertent doping and new emerging doping agents is constantly conducted. By way of reviewing and summarizing, this annual banned-substance review evaluates the literature published between October 2018 and September 2019 offering an in-depth evaluation of developments in these arenas and their potential application to substances reported in WADA's 2019 Prohibited List.

Keywords: alternative matrices; doping; mass spectrometry; sport.

Publication types

  • Review

MeSH terms

  • Anabolic Agents / analysis
  • Anabolic Agents / blood
  • Anabolic Agents / urine
  • Animals
  • Doping in Sports*
  • Hormones / analysis
  • Hormones / blood
  • Hormones / urine
  • Humans
  • Intercellular Signaling Peptides and Proteins / analysis
  • Intercellular Signaling Peptides and Proteins / blood
  • Intercellular Signaling Peptides and Proteins / urine
  • Mass Spectrometry / methods
  • Performance-Enhancing Substances / analysis
  • Performance-Enhancing Substances / blood
  • Performance-Enhancing Substances / urine
  • Specimen Handling / methods
  • Steroids / analysis
  • Steroids / blood
  • Steroids / urine
  • Substance Abuse Detection / methods*

Substances

  • Anabolic Agents
  • Hormones
  • Intercellular Signaling Peptides and Proteins
  • Performance-Enhancing Substances
  • Steroids