Himalayan glaciers have long been the focus of glaciologists across the world while trying to understand the contrasting patterns of elevation and mass changes. However, with limited number of ground observations, a comprehensive assessment of mass balance on a regional scale still remains elusive. Using the synoptic coverage of remote sensing data, we estimate a detailed spatial variation of glacier ice thickness change in the Central Himalaya of Uttarakhand using geodetic method, on a catchment scale. High resolution TerraSAR-X/TanDEM-X (12 m) and SRTM (30 m) digital elevation models (DEMs) have been utilized. The mean elevation change in the catchments is found to be -9.56 ± 0.2 m (mean annual elevation change rate is -0.68 ± 0.01 m a-1). To highlight the water potential of this region, the total ice mass loss has been estimated to be 16.0 ± 1.2 Gigatonne (Gt) from 2000-2014 from eight identified catchments namely Yamunotri, Bhagirathi, Mandakini, Alaknanda, Dhauliganga, Pindar, Goriganga and Kali/Sarda. The estimated mass balance has been validated using reported observations on five selective glaciers and the coefficient of determination is 0.93. This spatial variation of ice thickness estimated in the eight catchments is critical, as the melt-water from these glaciers contribute to the upper Ganga basin.