The Skin and Gut Microbiome and Its Role in Common Dermatologic Conditions

Samantha R Ellis; Mimi Nguyen; Alexandra R Vaughn; Manisha Notay; Waqas A Burney; Simran Sandhu; Raja K Sivamani

doi:10.3390/microorganisms7110550

The Skin and Gut Microbiome and Its Role in Common Dermatologic Conditions

Microorganisms. 2019 Nov 11;7(11):550. doi: 10.3390/microorganisms7110550.

Authors

Samantha R Ellis^{1

2}, Mimi Nguyen³, Alexandra R Vaughn², Manisha Notay², Waqas A Burney^{2

4}, Simran Sandhu³, Raja K Sivamani^{2

4

5

6

7}

Affiliations

¹ PotozkinMD Skincare Center, Danville, CA 94526, USA.
² Department of Dermatology, University of California-Davis, Sacramento, CA 95816, USA.
³ School of Medicine, University of California-Davis, Sacramento, CA 95817, USA.
⁴ Department of Biological Sciences, California State University, Sacramento, CA 95819, USA.
⁵ College of Medicine, California Northstate University, Elk Grove, CA 95757, USA.
⁶ Pacific Skin Institute, Sacramento, CA 95815, USA.
⁷ Zen Dermatology, Sacramento, CA 95819, USA.

Abstract

Microorganisms inhabit various areas of the body, including the gut and skin, and are important in maintaining homeostasis. Changes to the normal microflora due to genetic or environmental factors can contribute to the development of various disease states. In this review, we will discuss the relationship between the gut and skin microbiome and various dermatological diseases including acne, psoriasis, rosacea, and atopic dermatitis. In addition, we will discuss the impact of treatment on the microbiome and the role of probiotics.

Keywords: acne; atopic dermatitis; gut; microbiome; psoriasis; rosacea; skin.

Publication types

Review