LOW DOSE BATH FROM IMPT VS. IMXT FOR THE PELVIC AREA WHEN TREATING ADVANCED PROSTATE CANCER

Matěj Navrátil; Vladimír Vondráček; Michal Andrlík; Jiří Kubeš; Jozef Rosina; Alexander Grebenyuk

doi:10.1093/rpd/ncz235

LOW DOSE BATH FROM IMPT VS. IMXT FOR THE PELVIC AREA WHEN TREATING ADVANCED PROSTATE CANCER

Radiat Prot Dosimetry. 2019 Dec 31;186(2-3):377-380. doi: 10.1093/rpd/ncz235.

Authors

Matěj Navrátil^{1

2}, Vladimír Vondráček^{1

2}, Michal Andrlík^{1

2}, Jiří Kubeš^{1

2}, Jozef Rosina², Alexander Grebenyuk³

Affiliations

¹ Proton Therapy Center Czech, Budínova 1a, 18000 Prague 8, Czech Republic.
² Department of Health Care Disciplines and Population Protection, Faculty of Biomedical Engineering, Czech Technical University in Prague, Sítná square 3105, 272 01 Kladno, Czech Republic.
³ Department of Health Protection and Disaster Medicine, Pavlov First Saint Petersburg State Medical University, L'va Tolstogo str. 6-8, 197022 Saint Petersburg, Russia.

PMID: 31711189
DOI: 10.1093/rpd/ncz235

Abstract

Twenty (10 intensity-modulated proton therapy (IMPT) and 10 intensity-modulated x-ray therapy (IMXT) treatment plans for patients with advanced prostate carcinoma were compared in this study. All chosen patients were indicated for prostate and pelvic lymph nodes irradiation using simultaneous integrated boost technique. These patients represent typical specimen for this diagnose. IMPT irradiates just half of the tissue volume with a low dose (up to 10 cobalt gray equivalent) compared to IMXT without compromise in target volumes coverage and in this way reduces the risk of secondary cancer development or other possible complications.

Publication types

Comparative Study

MeSH terms

Humans
Lymph Nodes / radiation effects*
Male
Organs at Risk / radiation effects
Pelvis / radiation effects*
Prostatic Neoplasms / radiotherapy*
Proton Therapy / methods*
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted / methods*
Radiotherapy, Intensity-Modulated / methods*
X-Ray Therapy / methods*