Sclerosing Mesenteritis Mimicking IgG4-related Disease

Intern Med. 2020 Feb 15;59(4):513-518. doi: 10.2169/internalmedicine.3221-19. Epub 2019 Nov 8.

Abstract

A 72-year-old man was followed as an outpatient at our hospital for 6 years after surgery for small cell carcinoma of left adrenal gland origin. Follow-up abdominal computed tomography showed a 6-cm mass in the left lower mesentery. The patient underwent open laparotomy. The histological diagnosis was sclerosing mesenteritis. The previous specimens of the left adrenal mass were then re-examined with a microscope, and panniculitis was found around the small cell carcinoma. Both lesions were histologically similar to IgG4-related disease (RD), but they did not completely meet the diagnostic criteria of IgG4-RD clinically or histologically.

Keywords: IgG4-related disease; panniculitis; sclerosing mesenteritis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Diagnosis, Differential
  • Female
  • Humans
  • Immunoglobulin G4-Related Disease / diagnosis*
  • Immunoglobulin G4-Related Disease / physiopathology*
  • Immunoglobulin G4-Related Disease / surgery*
  • Laparotomy / methods
  • Male
  • Mesentery / physiopathology*
  • Mesentery / surgery*
  • Middle Aged
  • Molecular Mimicry
  • Panniculitis, Peritoneal / diagnosis*
  • Panniculitis, Peritoneal / pathology
  • Panniculitis, Peritoneal / surgery*
  • Tomography, X-Ray Computed / methods