Why do patients die after status epilepticus?

Epilepsy Behav. 2019 Dec;101(Pt B):106567. doi: 10.1016/j.yebeh.2019.106567. Epub 2019 Nov 8.

Abstract

The epidemiology of status epilepticus (SE) and predictors of outcome in particular have been well described with consistent findings around the world. Understanding of the actual causes of death in patients hospitalized with SE is limited. The following is a summary of published information about causes of death in patients hospitalized with SE and a reconciling of conflicting studies examining the influence of continuous intravenous anesthetic drugs on the mortality of SE. A recently published paper was presented at the Colloquium and is summarized here, along with new data addressing an audience question about withdrawal of care in SE. In the spirit of the conference, we end with a call to arms and invitation for collaborators. Proceedings of the 7th London-Innsbruck Colloquium on Status Epilepticus and Acute Seizures.

Keywords: Anesthetic; Causes of death; Status epilepticus; Withdrawal of life sustaining treatment.

Publication types

  • Review

MeSH terms

  • Anesthesia, Intravenous / adverse effects*
  • Anesthetics, Intravenous / adverse effects*
  • Cause of Death
  • Hospitalization
  • Humans
  • Status Epilepticus / chemically induced
  • Status Epilepticus / mortality*

Substances

  • Anesthetics, Intravenous