Comparison of Weight Loss in Sleeve Gastrectomy Patients With and Without Antrectomy: a Prospective Randomized Study

Obes Surg. 2020 Feb;30(2):446-450. doi: 10.1007/s11695-019-04177-9.

Abstract

Background: Laparoscopic sleeve gastrectomy (LSG) restricts gastric volume to achieve weight loss. We aimed to compare the efficacy of LSG with and without antrectomy for achieving weight loss.

Methods: The prospective randomized study comprised 127 obese patients that underwent either LSG with antrectomy (2 cm to pylorus) (group 1) or LSG without antrectomy (6 cm to pylorus) (group 2), using 36 Fr and 32 Fr bougies, respectively. Patients were examined at 3-, 6-, 12-, and 24-month intervals for body mass index (BMI) measurements.

Results: Overall, 66 (51%) and 57 (49%) of patients were assigned to groups 1 and 2, respectively. The mean BMI of group 1 patients were 49.5 ± 8.01, 35.8 ± 5.40, 31.3 ± 4.9, 26.7 ± 4.02, and 22.9 ± 4.01 at the baseline, 3rd, 6th, 12th, and 24th month, respectively. The decreases in BMI were statistically significant. The mean BMI of group 2 patients were 46.7 ± 7.06, 39.3 ± 6.04, 32.4 ± 5.01, 26.6 ± 3.76, and 21.6 ± 3.70 at baseline, 3rd, 6th, 12th, and 24th month, respectively. The differences were also statistically significant. When compared with group 2, group 1 patients showed significantly lower BMI values on the 3rd month. Other differences were not statistically significant.

Conclusion: LSG with or without antrectomy is safe and effective for weight loss. Larger studies are required to identify patients likely to benefit from LSG with antrectomy.

Keywords: Antral resection; BMI; Bariatric surgery; Sleeve gastrectomy.

Publication types

  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Azerbaijan
  • Body Mass Index
  • Female
  • Gastrectomy / adverse effects
  • Gastrectomy / methods*
  • Gastric Stump / pathology
  • Gastric Stump / surgery
  • Humans
  • Laparoscopy / adverse effects
  • Laparoscopy / methods
  • Male
  • Middle Aged
  • Obesity, Morbid / pathology
  • Obesity, Morbid / surgery*
  • Organ Size
  • Prospective Studies
  • Pyloric Antrum / pathology
  • Pyloric Antrum / surgery*
  • Treatment Outcome
  • Weight Loss / physiology*