The application of personal glucose meters as universal point-of-care diagnostic tools

Fabio Lisi; Joshua R Peterson; J Justin Gooding

doi:10.1016/j.bios.2019.111835

The application of personal glucose meters as universal point-of-care diagnostic tools

Biosens Bioelectron. 2020 Jan 15:148:111835. doi: 10.1016/j.bios.2019.111835. Epub 2019 Nov 2.

Authors

Fabio Lisi¹, Joshua R Peterson¹, J Justin Gooding²

Affiliations

¹ School of Chemistry, The Australian Centre for NanoMedicine and ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, The University of New South Wales, Sydney 2052, Australia.
² School of Chemistry, The Australian Centre for NanoMedicine and ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, The University of New South Wales, Sydney 2052, Australia. Electronic address: justin.gooding@unsw.edu.au.

PMID: 31707326
DOI: 10.1016/j.bios.2019.111835

Abstract

Personal glucose meters (PGMs) have been used for the measurement of blood glucose for decades now such that they have become the most used analytical method in the world. They are also well placed to be repurposed for point-of-care testing of other analytes as they are inexpensive, portable and quantitative. Efforts to repurpose PGMs for the detection of any analyte at the point-of-care have been one focus of biosensor research for several years now with a number of successful efforts in the detection of a wide range of analytes. This article reviews the published methods to repurpose a PGM to detect analytes other than glucose, and analyses the potential and the challenges to be overcome in developing a PGM-based biosensor and bring it to market.

Keywords: Biosensor; Competitive immunoassay; Functional nucleic acid sensors; Personal glucose meter; Point of care; Sandwich immunoassay.

Publication types

Review

MeSH terms

Animals
Biosensing Techniques / instrumentation*
Biosensing Techniques / methods
Blood Glucose / analysis*
Blood Glucose Self-Monitoring / instrumentation*
Blood Glucose Self-Monitoring / methods
Humans
Point-of-Care Systems*

Substances

Blood Glucose