Development of Neuroimaging-Based Biomarkers in Psychiatry

Adv Exp Med Biol. 2019:1192:159-195. doi: 10.1007/978-981-32-9721-0_9.

Abstract

This chapter presents an overview of accumulating neuroimaging data with emphasis on translational potential. The subject will be described in the context of three disease states, i.e., schizophrenia, bipolar disorder, and major depressive disorder, and for three clinical goals, i.e., disease risk assessment, subtyping, and treatment decision.

Keywords: Amygdala; Biomarker; Bipolar disorder; Connectomics; Depression; Diagnosis; Diffusion tensor imaging; Functional magnetic resonance imaging; Gray matter; Hippocampus; Machine learning; Magnetic resonance imaging; Neuroimaging; Personalized; Positron emission tomography; Predictive; Prefrontal cortex; Prognosis; Schizophrenia; Voxel-based morphometry; White matter.

Publication types

  • Review

MeSH terms

  • Biomarkers
  • Bipolar Disorder / diagnostic imaging*
  • Brain / diagnostic imaging*
  • Clinical Decision-Making
  • Depressive Disorder, Major / diagnostic imaging*
  • Humans
  • Magnetic Resonance Imaging
  • Neuroimaging*
  • Psychiatry*
  • Risk Assessment
  • Schizophrenia / diagnostic imaging*

Substances

  • Biomarkers