Long-term experience of atrioventricular node ablation in patients with refractory atrial arrhythmias

Heart Vessels. 2020 May;35(5):699-704. doi: 10.1007/s00380-019-01536-5. Epub 2019 Nov 8.

Abstract

Atrial fibrillation and other atrial tachyarrhythmias are increasing with age and concomitant morbidity. First options in symptomatic patients are drug treatment and catheter ablation. Nevertheless, a considerable number of patients suffer from refractory atrial tachyarrhythmias despite treatment. Atrioventricular node ablation (AVNA) may be helpful in many of these patients. Therefore, we investigated AVNA patients with a long-term follow-up. We enrolled 82 patients with a follow-up longer than 1 year receiving AVNA for drug- and ablation-resistant atrial tachyarrhythmias (AA) in a retrospective manner. Mean follow-up duration was 48 ± 24 months. 50% of the patients initially received AVNA to optimize biventricular pacing in cardiac resynchronization therapy, the other 50% because of refractory symptomatic tachyarrhythmias. Persistent AV block was achieved in every patient. Symptom relief and patient satisfaction were high during follow-up. Due to system upgrades there were 63% of patients with a biventricular system during follow-up. In these patients, left-ventricular ejection fraction (LV-EF) increased by 7% (42-49%) after ablation. AVNA is effective in increasing biventricular pacing as well as for symptom relief in patients with refractory atrial tachyarrhythmias. AVNA should be considered as a valuable option in patients with refractory atrial tachyarrhythmias lacking other treatment options.

Keywords: Atrial fibrillation; Atrioventricular node ablation; Cardiac pacing.

MeSH terms

  • Action Potentials
  • Aged
  • Aged, 80 and over
  • Atrial Fibrillation / diagnosis
  • Atrial Fibrillation / physiopathology
  • Atrial Fibrillation / surgery*
  • Atrioventricular Node / physiopathology
  • Atrioventricular Node / surgery*
  • Catheter Ablation* / adverse effects
  • Databases, Factual
  • Female
  • Heart Rate
  • Humans
  • Male
  • Middle Aged
  • Patient Satisfaction
  • Recovery of Function
  • Retrospective Studies
  • Tachycardia, Supraventricular / diagnosis
  • Tachycardia, Supraventricular / physiopathology
  • Tachycardia, Supraventricular / surgery*
  • Time Factors
  • Treatment Outcome
  • Ventricular Function, Left