The next steps in curing Alzheimer's disease

Prog Mol Biol Transl Sci. 2019:168:219-221. doi: 10.1016/bs.pmbts.2019.06.014. Epub 2019 Jun 29.

Abstract

The Alzheimer's disease (AD) field urgently needs new ideas. I offer here a number of thoughts focusing on the combination of the cellular phase of AD and new bionic techniques. These techniques enable to answer alternative hypotheses raised and help to unravel the multifactorial mechanisms initiating Alzheimer's disease.

Keywords: Aducanumab; Bionic techniques; Molecular misreading; Protein quality control; RNA; Ubiquitin.

Publication types

  • Review

MeSH terms

  • Alzheimer Disease / pathology*
  • Alzheimer Disease / therapy*
  • Animals
  • Humans
  • Molecular Targeted Therapy*