Relationships between Metabolic Comorbidities and Occurrence, Severity, and Outcomes in Patients with Acute Pancreatitis: A Narrative Review

Biomed Res Int. 2019 Oct 7:2019:2645926. doi: 10.1155/2019/2645926. eCollection 2019.

Abstract

Background. The population of patients with acute pancreatitis treated by the staff at our department of gastroenterology includes those with mild and self-limited disease ranging to those with severe and fatal disease. Early diagnosis and accurate prediction of the severity and outcome of this disease, which is commonly seen by our department, is important for a successful outcome. Metabolic comorbidities (e.g., diabetes mellitus, fatty liver, obesity, and metabolic syndrome) are relevant to the severity and progression of many diseases. The objective of this review was to examine clinical relationships between metabolic comorbidities and occurrence, severity, and outcome of acute pancreatitis.

Publication types

  • Review

MeSH terms

  • Animals
  • Comorbidity
  • Humans
  • Metabolic Syndrome / metabolism*
  • Metabolic Syndrome / pathology*
  • Pancreatitis / metabolism*
  • Pancreatitis / pathology*
  • Prognosis
  • Severity of Illness Index