Continuous glucose monitoring in cystic fibrosis - A practical guide

Christine L Chan; Katie Larson Ode; Andrea Granados; Amir Moheet; Antoinette Moran; Shihab Hameed

doi:10.1016/j.jcf.2019.08.025

Continuous glucose monitoring in cystic fibrosis - A practical guide

J Cyst Fibros. 2019 Oct:18 Suppl 2:S25-S31. doi: 10.1016/j.jcf.2019.08.025.

Authors

Christine L Chan¹, Katie Larson Ode², Andrea Granados³, Amir Moheet⁴, Antoinette Moran⁵, Shihab Hameed⁶

Affiliations

¹ Department of Pediatrics, Children's Hospital Colorado, University of Colorado, Aurora, CO, USA. Electronic address: Christinel.chan@childrenscolorado.org.
² Department of Pediatrics, University of Iowa Stead Family Children's Hospital, Iowa City, IA, USA; Fraternal Order of Eagles Diabetes Research Center, University of Iowa, Iowa City, IA, USA.
³ Department of Pediatrics, Washington University School of Medicine in St. Louis, MO, USA.
⁴ Department of Medicine, University of Minnesota, Minneapolis, MN, USA.
⁵ Department of Pediatrics, University of Minnesota, Minneapolis, MN, USA.
⁶ University of New South Wales, Australia; Sydney Children's Hospital, Randwick, Australia; University of Sydney, Australia; Royal North Shore Hospital, St Leonards, NSW, Australia.

PMID: 31679725
DOI: 10.1016/j.jcf.2019.08.025

Abstract

Our ability to monitor blood glucose levels has become increasingly accurate over the last few decades. Continuous glucose monitoring (CGM) technology now allows providers and patients the ability to monitor glucose levels retrospectively as well as in real-time for diabetes management. CGM also provides the ability to study glucose patterns and trends for insight into the pathophysiology and natural history of disease. CGM captures a more complete picture of glucose profiles than traditional measures of glycemia such as the hemoglobin A1c or self-monitoring of blood glucose levels. This article provides a review of the history of glucose monitoring, a review of the literature pertaining to CGM with a focus on studies in patients with cystic fibrosis, and discusses practical uses of CGM technology and its application for the evaluation and management of cystic fibrosis related diabetes.

Keywords: Artificial pancreas; Continuous glucose monitoring; Cystic fibrosis related diabetes.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Blood Glucose / analysis*
Blood Glucose Self-Monitoring* / instrumentation
Cystic Fibrosis / blood*
Cystic Fibrosis / complications*
Diabetes Mellitus / blood*
Diabetes Mellitus / diagnosis
Diabetes Mellitus / etiology*
Equipment Design
Humans

Substances

Blood Glucose

Grants and funding

P30 DK054759/DK/NIDDK NIH HHS/United States