Surgical Management of Dysplasia and Cancer in Inflammatory Bowel Disease

Surg Clin North Am. 2019 Dec;99(6):1111-1121. doi: 10.1016/j.suc.2019.08.006. Epub 2019 Sep 23.

Abstract

Patients with inflammatory bowel disease are at an increased risk of cancer secondary to long-standing intestinal inflammation. Surgical options must take into account the significant risk of synchronous disease at other colonic sites. Ileal pouch anal anastomosis is a viable option for patients with ulcerative colitis, but this should be restricted to early cancers that are unlikely to require preoperative or postoperative radiation treatment.

Keywords: Cancer; Crohn; Dysplasia; Ulcerative colitis.

Publication types

  • Review

MeSH terms

  • Anastomosis, Surgical
  • Cell Transformation, Neoplastic / pathology*
  • Colectomy / methods
  • Colitis, Ulcerative / epidemiology
  • Colitis, Ulcerative / pathology
  • Colitis, Ulcerative / surgery
  • Colorectal Neoplasms / epidemiology*
  • Colorectal Neoplasms / pathology*
  • Colorectal Neoplasms / surgery
  • Comorbidity
  • Crohn Disease / epidemiology
  • Crohn Disease / pathology
  • Crohn Disease / surgery
  • Female
  • Humans
  • Incidence
  • Inflammatory Bowel Diseases / epidemiology*
  • Inflammatory Bowel Diseases / pathology
  • Inflammatory Bowel Diseases / surgery*
  • Male
  • Precancerous Conditions / epidemiology
  • Precancerous Conditions / pathology*
  • Prognosis
  • Risk Assessment
  • Surgical Stomas
  • Survival Analysis