Utility of FilmArrayⓇ ME panel for prompt Neisseria meningitidis detection in non-cerebrospinal fluid samples- A case report

Paloma García-Clemente; Juan José Menéndez-Suso; Iker Falces-Romero; Luis Escosa-García; Cristina Schüffelmann; Emilio Cendejas-Bueno

doi:10.1016/j.jinf.2019.10.016

Utility of FilmArray^Ⓡ ME panel for prompt Neisseria meningitidis detection in non-cerebrospinal fluid samples- A case report

J Infect. 2020 Jan;80(1):121-142. doi: 10.1016/j.jinf.2019.10.016. Epub 2019 Oct 25.

Authors

Paloma García-Clemente¹, Juan José Menéndez-Suso², Iker Falces-Romero¹, Luis Escosa-García³, Cristina Schüffelmann², Emilio Cendejas-Bueno⁴

Affiliations

¹ Clinical Microbiology Department, Hospital La Paz, Hospital La Paz, Paseo de La Castellana 261, 28046 Madrid, Spain.
² Pediatric Intensive Care Unit, Hospital La Paz, Paseo de La Castellana 261, 28046 Madrid, Spain.
³ Pediatric Infectious and Tropical Diseases Department, Paseo de La Castellana 261, 28046 Madrid, Spain.
⁴ Clinical Microbiology Department, Hospital La Paz, Hospital La Paz, Paseo de La Castellana 261, 28046 Madrid, Spain. Electronic address: ecendejas77@gmail.com.

PMID: 31669378
DOI: 10.1016/j.jinf.2019.10.016

Abstract

The FilmArray^Ⓡ Meningitis/Encephalitis Panel detects the 14 most frequent pathogens causing meningitis and/or encephalitis. The use of FilmArray ME with non-validated samples is seldom published in the literature. We describe the case of a 3-year-old child, diagnosed with acute meningoencephalitis, in whom the FilmArray^Ⓡ ME technique successfully identified Neisseria meningitidis in both skin biopsy and whole blood samples.

Keywords: Filmarray(Ⓡ) ME panel; Neisseria meningitidis; Offlabel usefulness.

Publication types

Case Reports
Letter

MeSH terms

Child, Preschool
Encephalitis*
Humans
Meningitis*
Multiplex Polymerase Chain Reaction
Neisseria meningitidis* / genetics