Hypothermia among neonates admitted to the neonatal unit at a tertiary hospital in South Africa

J Perinatol. 2020 Mar;40(3):433-438. doi: 10.1038/s41372-019-0539-y. Epub 2019 Oct 30.

Abstract

Objectives: To determine the prevalence of hypothermia on admission and at 24 h of life in very low birth weight infants (VLBWI) and associated morbidity and mortality.

Study design: Hospital records of VLBWI admitted to a neonatal unit were reviewed for information on patient's body temperature, clinical characteristics and mortality. Comparisons between normothermic and hypothermic VLBWI were performed.

Results: Mean gestational age and birth weight of enrolled infants were 29 ± 3 weeks and 1140 ± 253 g, respectively. Prevalence of admission hypothermia was 46.1%, with 38% developing hypothermia within 24-h following admission. VLBWI with hypothermia were more likely to have been born vaginally [aOR 2.85 (1.37-5.91)], have a birth weight < 1000 g [aOR 2.28 (1.25-4.16)], required resuscitation at birth [aOR 2.20 (1.23-3.94)], develop metabolic acidosis [aOR 3.04 (1.35-6.84)] and die within the first week of life [aOR 4.79 (1.43-16.02)].

Conclusions: Prevalence of hypothermia in VLBWI is high and is associated with poor outcomes.

MeSH terms

  • Body Temperature
  • Gestational Age
  • Humans
  • Hypothermia / complications
  • Hypothermia / epidemiology*
  • Infant, Newborn
  • Infant, Premature*
  • Infant, Premature, Diseases / epidemiology*
  • Infant, Premature, Diseases / mortality
  • Infant, Very Low Birth Weight*
  • Intensive Care Units, Neonatal
  • Patient Acuity
  • Prevalence
  • South Africa
  • Tertiary Care Centers