A case report of photodermatoses induced by the antifungal drug terbinafine

Eur J Hosp Pharm. 2019 Sep;26(5):288-289. doi: 10.1136/ejhpharm-2018-001683. Epub 2018 Dec 17.

Abstract

Terbinafine is an antifungaldrug(inhibitor of ergosterol synthesis) known to induce skin reactions. A 58-year-old female was treated with terbinafine for onychomycosis. On the fifth day of treatment a skin rash emerged on her sun-exposed areas. Biological testing did not find any allergic signs. Other skin reactions are well known with terbinafine, but we depict here, a case of photosensitisation induced by treatment, generally unknown for this antifungal. This side effect can be prevented by medication reconciliation and pharmaceutical advice from the clinical pharmacist.

Keywords: clinical pharmacist; drug-induced photosensitivity; medication reconciliation; pharmaceutical advice; terbinafine.

Publication types

  • Case Reports