Sagliker syndrome in a patient with end-stage renal disease with secondary hyperparathyroidism

Muhammad Ajmal Panezai; Sana Ahmed; Gates B Colbert

doi:10.1080/08998280.2019.1624092

Sagliker syndrome in a patient with end-stage renal disease with secondary hyperparathyroidism

Proc (Bayl Univ Med Cent). 2019 Jul 15;32(4):624-626. doi: 10.1080/08998280.2019.1624092. eCollection 2019 Oct.

Authors

Muhammad Ajmal Panezai¹, Sana Ahmed², Gates B Colbert²

Affiliations

¹ Department of Internal Medicine, Baylor University Medical Center at DallasDallasTexas.
² Division of Nephrology, Department of Internal Medicine, Baylor University Medical Center at DallasDallasTexas.

Abstract

Sagliker syndrome (SS), also known as an "uglifying human face syndrome," is one of the severe manifestations of chronic kidney disease in patients with uncontrolled secondary hyperparathyroidism. Patients with SS develop short stature, maxillary and mandibular bone overgrowth, nasal bone and cartilage destruction, widely spaced teeth with anterior positioning, soft tissue tumors in the oral cavity, auditory loss, and neurological and psychological features. SS can possibly be prevented with proper treatment of secondary hyperparathyroidism using disease-modifying medication and surgical therapies. We report a case of SS in a patient in the USA with end-stage renal disease achieving adequate hemodialysis.

Keywords: Chronic kidney disease; Sagliker syndrome; end-stage renal disease; secondary hyperparathyroidism.

Publication types

Case Reports