Trapping endothelin-1 to hunt down cardiovascular disease?

Drug Discov Today. 2019 Nov;24(11):2108-2110. doi: 10.1016/j.drudis.2019.10.007. Epub 2019 Oct 22.

Authors

Bernhard Wernly¹, Christian Jung²

Affiliations

¹ Clinic of Internal Medicine II, Department of Cardiology, Paracelsus Medical University of Salzburg, Salzburg, Austria.
² Division of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, University Duesseldorf, Duesseldorf, Germany. Electronic address: christian.jung@med.uni-duesseldorf.de.

PMID: 31654816
DOI: 10.1016/j.drudis.2019.10.007

No abstract available

Publication types

Editorial

MeSH terms

Cardiovascular Diseases / drug therapy*
Cardiovascular Diseases / metabolism*
Endothelin Receptor Antagonists / administration & dosage
Endothelin Receptor Antagonists / adverse effects
Endothelin Receptor Antagonists / therapeutic use*
Endothelin-1 / antagonists & inhibitors*
Endothelin-1 / genetics
Endothelium, Vascular / drug effects
Endothelium, Vascular / metabolism
Humans
Receptor, Endothelin A / genetics
Receptor, Endothelin A / metabolism*

Substances

Endothelin Receptor Antagonists
Endothelin-1
Receptor, Endothelin A