Wilson's disease presentation resembling autoimmune hepatitis

BMJ Case Rep. 2019 Oct 25;12(10):e230721. doi: 10.1136/bcr-2019-230721.

Abstract

We report a case of a 25-year-old female patient who showed chronic hepatopathy with elevated levels of autoantibodies and gamma globulins, resembling autoimmune hepatitis. After 8 weeks of unsuccessful immunosuppressive treatment, further evaluation showed laboratorial and histological findings suggestive of Wilson's disease. The new treatment with D-penicillamine resulted in positive outcome, despite the initial misleading diagnosis.

Keywords: hepatitis other; liver disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chelating Agents / therapeutic use
  • Diagnosis, Differential
  • Female
  • Hepatitis, Autoimmune / diagnosis
  • Hepatolenticular Degeneration / diagnosis*
  • Hepatolenticular Degeneration / drug therapy*
  • Humans
  • Penicillamine / therapeutic use

Substances

  • Chelating Agents
  • Penicillamine