Behavioral inhibition and EEG delta-beta correlation in early childhood: Comparing a between-subjects and within-subjects approach

Abstract

Heightened delta-beta correlation has been conceptualized as reflecting exaggerated neural regulation and has been implicated in anxiety. Behavioral inhibition (BI) is a temperament characterized by wariness to novelty and is a robust predictor of anxiety, but delta-beta correlation has not been investigated in relation to childhood BI. We examined the relation between BI and between-subjects (i.e., across participants) and within-subjects (i.e., across data epochs) measures of baseline EEG delta-beta correlation in 118 children. Using a between-subjects measure, children scoring high on BI had higher delta-beta correlation relative to low BI children at frontal and central, and marginally higher in parietal, brain regions. Using a within-subjects measure, continuous BI scores were positively correlated with central and parietal delta-beta correlation. Delta-beta correlation may be a neural correlate of BI in childhood that displays differences in region specificity, correlation strength, and variability of correlation values when comparing between- and within-subjects measures.

Keywords: Behavioral inhibition; Child; Delta-beta correlation; EEG; Temperament.