A Rare Complication: Development of an Aspergilloma after Endobronchial Coil Placement in a COPD Patient

Respiration. 2020;99(5):423-425. doi: 10.1159/000503363. Epub 2019 Oct 17.

Abstract

Endobronchial coils are a relatively novel endoscopic lung volume reduction modality that aims to increase functional capacity in chronic obstructive pulmonary disease (COPD) patients. Two major trials have studied the safety and efficacy of this therapy, but long-term safety has not been studied. Adverse events reported are mainly periprocedural pneumothoraces and early bacterial infectious complications. We report the case of a patient with severe emphysema (Global Initiative for Chronic Obstructive Lung Disease stage IV COPD) who developed endobronchial coil-associated aspergillomas 3 years after coil placement.

Keywords: Aspergilloma; Bronchoscopic lung volume reduction; COPD; Endobronchial coils.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Antifungal Agents / therapeutic use
  • Bronchoscopy*
  • Culture Techniques
  • Forced Expiratory Volume
  • Foreign Bodies / diagnostic imaging*
  • Humans
  • Male
  • Pneumonectomy*
  • Precipitin Tests
  • Pulmonary Aspergillosis / diagnosis
  • Pulmonary Aspergillosis / diagnostic imaging*
  • Pulmonary Aspergillosis / drug therapy
  • Pulmonary Emphysema / physiopathology
  • Pulmonary Emphysema / surgery*
  • Severity of Illness Index
  • Surgical Instruments*
  • Surgical Wound Infection / diagnosis
  • Surgical Wound Infection / diagnostic imaging*
  • Surgical Wound Infection / drug therapy
  • Tomography, X-Ray Computed
  • Voriconazole / therapeutic use

Substances

  • Antifungal Agents
  • Voriconazole